中文别名

人血清白蛋白

产品应用

WB, IHC-P, IHC-F, IF, ELISA

交叉反应

Human, Mouse, Rat, Goat (predicted: Dog)

抗体来源

Rabbit

免疫原

human Serum albumin puritied

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Polyclonal

理论分子量

69 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 0.02% Proclin300 and 50% Glycerol.

亚细胞定位

Secreted.

组织特异性

Plasma.

翻译后修饰

Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.

疾病

Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

相似性

Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.

SWISS

P02768

Gene ID

213

功能

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.